South African Health Products Regulatory Authority (SAHPRA) Medicines Registration Officer: Pre-Registration Vacancy 2026 | Salary: R562,800 - R681,300 per annum

Opportunity Overview

The South African Health Products Regulatory Authority (SAHPRA) is the National Medicines Regulatory Authority, established under the Medicines and Related Substances Act, 101 of 1965. SAHPRA is responsible for monitoring, evaluating, regulating, investigating, inspecting, registering, and controlling medicines, scheduled substances, clinical trials, and medical devices in the public interest.

This opportunity is for a Medicines Registration Officer within the Pre-Registration (Pharmaceutical Evaluation Management) unit. This is a contract position based in Pretoria, with the contract running until 31 March 2028, and offers an annual salary ranging from R562,800.00 to R681,300.00 (Total Cost to Company).

Minimum Requirements

• Matric certificate.
• A four-year Bachelor of Pharmacy degree (NQF Level 8) OR an Honours degree in a related health sciences field (NQF Level 8) as recognised by the South African Qualification Authority (SAQA).
• Registration with the South African Pharmacy Council (SAPC) is required for applicants with a Bachelor of Pharmacy degree.
• A valid driver’s licence.
• Experience Requirements:
• If Bachelor of Pharmacy (NQF Level 8): Minimum 2 years' relevant post-internship experience in pharmaceutical or related medicines regulation, or in medicines production quality assurance (experience gained outside SAHPRA). Alternatively, at least 1 year of relevant experience within SAHPRA.
• If Honours degree in a related Health Sciences field (NQF Level 8): Minimum 3 years' relevant experience in pharmaceutical or related medicines regulation, or in medicines production quality assurance (experience gained outside SAHPRA). Alternatively, at least 1 year of relevant experience within SAHPRA.
• A relevant master’s degree qualification at NQF Level 9, as recognised by SAQA, will be considered an added advantage.

Key Responsibilities

• Evaluate new applications and conduct peer reviews of applications for medicine registration.
• Generate evaluation reports for new applications (new chemical entities and generics) in compliance with required templates and adopted regulatory/scientific standards.
• Amend evaluation reports following the peer-review process to generate a list of queries for the applicant.
• Peer review primary reports compiled by other reviewers.
• Prepare reports for internal working groups and, where necessary, present findings at the advisory committee for complex scientific matters.
• Prepare query letters to applicants.
• Prepare a basis for the approval or rejection of applications.
• Provide quality assurance of reports and facilitate resolutions on technical matters.
• Evaluate applicant responses for the registration/approval of medicines.
• Generate second (and subsequent) evaluation reports for response applications and submit for peer review.
• Amend response reports following the peer-review process to generate queries for the applicant, if necessary.
• Peer review other evaluators’ response reports according to required templates and adopted regulatory/scientific standards.

How to Apply

Interested applicants should submit their applications online via the SAHPRA vacancies portal.

• Apply Online: http://www.sahpra.org.za/vacancies
• The closing date for applications is 31 March 2028.
• This position is based in Pretoria.